Developing and functionalizing peptide and protein assemblies
- Jiang T, Magnotti EL, Conticello VP. Geometrical frustration as a potential design principle for peptide-based assemblies. Interface Focus. 2017 Dec 6;7(6):20160141. doi: 10.1098/rsfs.2016.0141. Epub 2017 Oct 20. PMID: 29147554; PMCID: PMC5665794.
- Conticello V, Hughes S, Modlin C. Biomaterials Made from Coiled-Coil Peptides. Subcell Biochem. 2017;82:575-600. doi: 10.1007/978-3-319-49674-0_17. PMID: 28101873; PMCID: PMC7121611.
- Magnotti EL, Hughes SA, Dillard RS, Wang S, Hough L, Karumbamkandathil A, Lian T, Wall JS, Zuo X, Wright ER, Conticello VP. Self-Assembly of an α-Helical Peptide into a Crystalline Two-Dimensional Nanoporous Framework. J Am Chem Soc. 2016 Dec 21;138(50):16274-16282. doi: 10.1021/jacs.6b06592. Epub 2016 Dec 12. PMID: 27936625; PMCID: PMC5739522.https://pubs.acs.org/doi/10.1021/jacs.6b06592
- Magnotti E, Conticello V. Two-Dimensional Peptide and Protein Assemblies. Adv Exp Med Biol. 2016;940:29-60. doi: 10.1007/978-3-319-39196-0_3. PMID: 27677508.
- DiMaio F, Song Y, Li X, Brunner MJ, Xu C, Conticello V, Egelman E, Marlovits T, Cheng Y, Baker D. Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement. Nat Methods. 2015 Apr;12(4):361-365. doi: 10.1038/nmeth.3286. Epub 2015 Feb 23. PMID: 25707030; PMCID: PMC4382417.https://www.nature.com/articles/nmeth.3286
- Xu C, Liu R, Mehta AK, Guerrero-Ferreira RC, Wright ER, Dunin-Horkawicz S, Morris K, Serpell LC, Zuo X, Wall JS, Conticello VP. Rational design of helical nanotubes from self-assembly of coiled-coil lock washers. J Am Chem Soc. 2013 Oct 16;135(41):15565-78. doi: 10.1021/ja4074529. Epub 2013 Oct 3. PMID: 24028069.https://pubs.acs.org/doi/10.1021/ja4074529
- Anzini P, Xu C, Hughes S, Magnotti E, Jiang T, Hemmingsen L, Demeler B, Conticello VP. Controlling self-assembly of a peptide-based material via metal-ion induced registry shift. J Am Chem Soc. 2013 Jul 17;135(28):10278-81. doi: 10.1021/ja404677c. Epub 2013 Jul 9. PMID: 23815081; PMCID: PMC3786573.https://pubs.acs.org/doi/10.1021/ja404677c
- Wu IL, Patterson MA, Carpenter Desai HE, Mehl RA, Giorgi G, Conticello VP. Multiple site-selective insertions of noncanonical amino acids into sequence-repetitive polypeptides. Chembiochem. 2013 May 27;14(8):968-78. doi: 10.1002/cbic.201300069. Epub 2013 Apr 26. PMID: 23625817; PMCID: PMC3786561.
Bettering nature’s macromolecular machines
- Jiang T, Conticello VP. Programmable Fabrication of Multilayer CollagenNanosheets of Defined Composition. Methods Mol Biol. 2018;1777:221-232. doi: 10.1007/978-1-4939-7811-3_13. PMID: 29744838.
- Jiang T, Meyer TA, Modlin C, Zuo X, Conticello VP, Ke Y. Structurally Ordered Nanowire Formation from Co-Assembly of DNA Origami and Collagen-Mimetic Peptides. J Am Chem Soc. 2017 Oct 11;139(40):14025-14028. doi: 10.1021/jacs.7b08087. Epub 2017 Oct 2. PMID: 28949522.
- Jiang T, Vail OA, Jiang Z, Zuo X, Conticello VP. Rational Design of Multilayer Collagen Nanosheets with Compositional and Structural Control. J Am Chem Soc. 2015 Jun 24;137(24):7793-802. doi: 10.1021/jacs.5b03326. Epub 2015 Jun 9. PMID: 26021882.
- Jiang T, Xu C, Zuo X, Conticello VP. Structurally homogeneous nanosheets from self-assembly of a collagen-mimetic peptide. Angew Chem Int Ed Engl. 2014 Aug 4;53(32):8367-71. doi: 10.1002/anie.201403780. Epub 2014 Jun 24. PMID: 24961508.
- Jiang T, Xu C, Liu Y, Liu Z, Wall JS, Zuo X, Lian T, Salaita K, Ni C, Pochan D, Conticello VP. Structurally defined nanoscale sheets from self-assembly of collagen-mimetic peptides. J Am Chem Soc. 2014 Mar 19;136(11):4300-8. doi: 10.1021/ja412867z. Epub 2014 Mar 10. PMID: 24571053.
Understanding nature’s macromolecular machines
- Sallach RE, Conticello VP, Chaikof EL. Expression of a recombinant elastin-like protein in pichia pastoris. Biotechnol Prog. 2009 Nov-Dec;25(6):1810-8. doi: 10.1002/btpr.208. PMID: 19827084; PMCID: PMC2796711.
- Sallach RE, Leisen J, Caves JM, Fotovich E, Apkarian RP, Conticello VP, Chaikof EL. A permanent change in protein mechanical responses can be produced by thermally-induced microdomain mixing. J Biomater Sci Polym Ed. 2009;20(11):1629-44. doi: 10.1163/156856208X386228. PMID: 19619402; PMCID: PMC2724671.